naltrexone targets OPRK1
Evidence from:
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all sources
Evidence (2 sources)
Naltrexone is a non-selective antagonist of mu, kappa, and delta opioid receptors
confidence: 0.98
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol.
(2012)
PMID:22954510
cited
activity at delta and kappa opioid receptors, in addition to mu, may underlie the effects of naltrexone on alcohol-related phenotypes
confidence: 0.85