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naltrexone targets OPRK1

Subject
naltrexone
Relation
targets
Object
OPRK1
p-value
Evidence from: primary | all sources

Evidence (2 sources)

Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review. (2018) PMID:30167705 cited
Naltrexone is a non-selective antagonist of mu, kappa, and delta opioid receptors
confidence: 0.98
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
activity at delta and kappa opioid receptors, in addition to mu, may underlie the effects of naltrexone on alcohol-related phenotypes
confidence: 0.85