OPRM1 biomarker_for heavy drinking

Subject: OPRM1
Relation: biomarker_for
Object: heavy drinking
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary

lower OPRM1 expression levels ... of heroin abusers compared to normal controls

confidence: 0.85

Gene expression in the addicted brain. (2014) PMID:25172478 cited

in heroin addicts, there was elevated methylation at several CpG sites in the promoter of a μ-opioid receptor gene, OPRM1

confidence: 0.75