NLGN3 risk_factor_for autism

Subject: NLGN3
Relation: risk_factor_for
Object: autism
p-value: —

Evidence from: primary | all sources

Evidence (4 sources)

Development of a high-throughput arrayed neural circuitry platform using human induced neurons for drug screening applications. (2020) PMID:32064487 cited

mutations in human neuroligin genes are implicated in neurodevelopmental disorders such as autism

confidence: 0.95

Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism. (2012) PMID:22511880 cited

as causes for nonsyndromic autism (e.g. NRXN1, NLGN3/4X, SHANK3)

confidence: 0.95

Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism. (2012) PMID:22511880 cited

genes ... as causes for nonsyndromic autism (e.g. NRXN1, NLGN3/4X, SHANK3)

confidence: 0.96

Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism. (2012) PMID:22511880 cited

Genes with essential roles in synaptic plasticity have been implicated as an important cause of autism (e.g. ... NLGN3/4X, ...)

confidence: 0.95