paperKB
coga / coga-kb
Processing
Help
Sign in

rs1229984 associated_with alcohol dependence

Subject
rs1229984
Relation
associated_with
Object
alcohol dependence
p-value
5e-08
Evidence from: primary | all sources

Evidence (6 sources)

Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. (2019) PMID:31090166 primary
rs1229984 in ADH1B was significantly associated with AD (p = 1.72E-8).
confidence: 0.96
Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. (2019) PMID:31090166 primary
for 2 of the 5 loci (rs1229984 ... meta-analyses across samples yielded more significant associations.
confidence: 0.95
Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. (2019) PMID:31090166 primary
detected genome-wide significant (GWS) association with rs1229984 (Europeans) ...
confidence: 0.95
Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. (2019) PMID:31090166 primary
for 2 of the 5 loci (rs1229984 and rs188227250), meta-analyses across samples yielded more significant associations
confidence: 0.90
The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood. (2017) PMID:27991676 primary
rs1229984 (Arg48His) on ADH1B ... identified and subsequently replicated in GWAS for its association with alcohol dependence across different populations.
confidence: 0.96
Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. (2014) PMID:23362995 primary
we have previously demonstrated that the missense SNP rs1229984 is associated with AD at p < 5×10−8
confidence: 0.95