Htr7 risk_factor_for alcohol dependence

Subject: Htr7
Relation: risk_factor_for
Object: alcohol dependence
p-value: 0.0074

Evidence from: primary | all sources

Evidence (8 sources)

Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary

significant joint-association to alcohol dependence (P = 0.0074)

confidence: 0.85

Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary

HTR7 also appears to play a role in the risk for alcohol dependence, with a significant association emerging ... rs7916403

confidence: 0.96

Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary

significant linkage peak ... for alcohol dependence in African-Americans ... a region that encompasses the HTR7 gene

confidence: 0.80

Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary

association signals observed at HTR7 ... indicate important genetic effects on ... the risk of alcohol dependence

confidence: 0.94

Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary

Omnibus tests ... revealed significant joint-haplotype association with alcohol dependence (P = 0.0074).

confidence: 0.85

Genome-wide association discoveries of alcohol dependence. (2014) PMID:25278008 cited

preceding ... HTR7 ... higher priority in risk for alcohol dependence

confidence: 0.90

Genome-wide association discoveries of alcohol dependence. (2014) PMID:25278008 cited

HTR7 ... were likely to play important roles in risk for alcohol dependence

confidence: 0.95

Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10. (2009) PMID:18930185 cited

genes ... potentially relevant to alcohol dependence, of which perhaps the most immediately interesting are ... HTR7

confidence: 0.85