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s allele risk_factor_for depression

Subject
s allele
Relation
risk_factor_for
Object
depression
p-value
Evidence from: primary | all sources

Evidence (4 sources)

The genetic basis of addictive disorders. (2012) PMID:22640768 cited
Carriers of the low-transcribing S allele exhibited more depression ... after stressful life events than L individuals.
confidence: 0.90
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. (2009) PMID:19531786 cited
we investigated the associations between stressful life events ... and the number of S alleles ... on depression as the response variable.
confidence: 0.90
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. (2009) PMID:19531786 cited
risk of depression increasing with the number of S alleles in the presence of stressful life events
confidence: 0.90
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. (2009) PMID:19531786 cited
Logistic regression models were used to test the associations between the explanatory (number of S alleles ...) and response variables (depression).
confidence: 0.92