APP interacts_with β-secretase

Subject: APP
Relation: interacts_with
Object: β-secretase
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells. (2016) PMID:27684569 cited

reduced the level of APP to interact with BACE1 and subsequent cleavage for Aβ production

confidence: 0.90

New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy. (2014) PMID:25368578 cited

APP cleavage enzymes such as β-secretase

confidence: 0.88