schizophrenia associated_with major depressive disorder

Subject: schizophrenia
Relation: associated_with
Object: major depressive disorder
p-value: 1.1e-40

Evidence from: primary | all sources

Evidence (3 sources)

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits. (2019) PMID:30962613 cited

joint analysis of GWAS summary statistics from five genetically correlated psychiatric case-control traits: schizophrenia, ... major depressive disorder (MDD), ...

confidence: 0.96

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. (2018) PMID:29700475 cited

significant bi-directional correlations in SNP effect sizes for schizophrenia loci in major depression (PGSMR=1.1×10−40)

confidence: 0.95

The psychiatric GWAS consortium: big science comes to psychiatry. (2010) PMID:20955924 cited

Cases with schizophrenia frequently have symptoms highly similar to those with ... major depressive disorder

confidence: 0.90