rs16969968 interacts_with rs578776

Subject: rs16969968
Relation: interacts_with
Object: rs578776
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. (2009) PMID:19132693 cited

In both samples, rs16969968, rs578776, rs1051730, rs2869546, and rs6495308 were partitioned in a single LD block.

confidence: 0.90

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

For rs16969968 and rs578776, r2 = 0.20 and |D′| = 1 in EAs; r2 = 0.07 and |D′| = 1 in AAs

confidence: 0.94