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GABA associated_with schizophrenia

Subject
GABA
Relation
associated_with
Object
schizophrenia
p-value
Evidence from: primary | all sources

Evidence (4 sources)

Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity. (2021) PMID:34291596 primary
role of GABA interneurons for various EEG oscillations in schizophrenia
confidence: 0.85
Mapping genomic loci implicates genes and synaptic biology in schizophrenia. (2022) PMID:35396580 cited
genes expressed in CNS neurons, both excitatory and inhibitory... neurons as the most important site of pathology.
confidence: 0.94
Cortical glutamic acid decarboxylase 67 deficiency results in lower cannabinoid 1 receptor messenger RNA expression: implications for schizophrenia. (2012) PMID:22036037 cited
Alterations in subpopulations of GABA neurons appear to contribute to dysfunction of the dorsolateral prefrontal cortex (DLPFC) in schizophrenia.
confidence: 0.92
Cortical glutamic acid decarboxylase 67 deficiency results in lower cannabinoid 1 receptor messenger RNA expression: implications for schizophrenia. (2012) PMID:22036037 cited
deficits in GABA-related transcripts in schizophrenia
confidence: 0.85