Chrna3 interacts_with nicotine

Subject: Chrna3
Relation: interacts_with
Object: nicotine
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Genetics of substance use disorders in the era of big data. (2021) PMID:34211176 cited

their protein products interact directly with nicotine

confidence: 0.96

Genetic and environmental contributions to the relationships between brain structure and average lifetime cigarette use. (2015) PMID:25690561 cited

Genes ... (CHRNA5, CHRNA3 and CHRNB4) alter receptor activity and sensitivity to nicotine

confidence: 0.90

Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited

involvement of the α3 ... subunits ... in response to nicotine

confidence: 0.92