ondansetron protective_against conditioned place preference
Evidence from:
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Evidence (2 sources)
From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics.
(2009)
PMID:19214139
cited
Ondansetron reduced the CPP induced by morphine in rodents
confidence: 0.90
From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics.
(2009)
PMID:19214139
cited
Mice receiving ondansetron 1 mg/kg with morphine displayed a mean difference of 0.40% (95% CI: -9.666‑10.47; P = 0.93). Thus, ondansetron completely blocked the place preference.
confidence: 0.92