APP regulates β-amyloid

Subject: APP
Relation: regulates
Object: β-amyloid
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. (2017) PMID:27926491 cited

Aβ is produced from APP through the sequential proteolytic action of β- and γ-secretases

confidence: 0.94