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rs1051730 associated_with nicotine

Subject
rs1051730
Relation
associated_with
Object
nicotine
p-value
6e-20
Evidence from: primary | all sources

Evidence (7 sources)

Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. (2013) PMID:23249876 cited
rs1051730 ... have been associated with nicotine dependence
confidence: 0.95
Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. (2013) PMID:23249876 cited
prior associations of rs1051730 with nicotine dependence
confidence: 0.90
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited
Both SNPs are located in regions that have been associated with smoking and nicotine dependence in European Americans
confidence: 0.85
Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011) PMID:21079997 cited
these SNPs are strongly associated with nicotine dependence
confidence: 0.96
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. (2009) PMID:19429911 cited
SNP rs1051730 ... was associated with ... nicotine dependence among smokers.
confidence: 0.98
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. (2009) PMID:19429911 cited
implicating the variant in nicotine dependence rather than smoking initiation.
confidence: 0.93
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. (2009) PMID:19132693 cited
we verified the association of ... rs1051730 with nicotine dependence when FTND scores were used as phenotype
confidence: 0.96