rs2072661 risk_factor_for relapse
Evidence from:
primary |
all sources
Evidence (3 sources)
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.
(2008)
PMID:18593715
cited
Two SNPs ... show a substantial impact on relapse at the EOT with an observed LRT P-value for rs2072661 of 9.97 × 10⁻⁴.
confidence: 0.94
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.
(2008)
PMID:18593715
cited
substantial increase in relapse rates for those individuals carrying the minor allele after they went off treatment
confidence: 0.85
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.
(2008)
PMID:18593715
cited
any haplotype without these minor alleles shows no effect further indicating that either rs2072661 or rs2072660 are driving the effect.
confidence: 0.85