NFIA regulates Nr3c1
Evidence from:
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Evidence (5 sources)
Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.
(2005)
PMID:16262207
cited
demethylation ... enhances NFIA binding to the exon 17 promoter, increasing GR gene transcription
confidence: 0.90
Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.
(2005)
PMID:16262207
cited
enhanced NGFIA binding to the exon 17 promoter increased hippocampal GR expression
confidence: 0.92
Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.
(2005)
PMID:16262207
cited
NGFIA response element in the exon 17 GR promoter
confidence: 0.85
Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.
(2005)
PMID:16262207
cited
NGFIA antisense completely blocks the effects of 5-HT on GR expression in hippocampal cell cultures.
confidence: 0.92
Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.
(2005)
PMID:16262207
cited
HDAC inhibition ... associated with enhanced NGFIA binding to the exon 17 promoter sequence and completely eliminates the effect of maternal care. As expected, enhanced NGFIA binding to the exon 17 promoter increased hippocampal GR expression.
confidence: 0.94