GABA interacts_with GABAA receptor
Evidence from:
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Evidence (4 sources)
Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism.
(2006)
PMID:17373405
primary
GABA interacts with complex protein molecules (i.e., receptors)... such as the GABAA ... receptor.
confidence: 0.94
GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures.
(2015)
PMID:26250693
cited
The fast inhibitory effect of GABA ... is mediated through GABA type-A (GABAA) receptors
confidence: 0.95
Impulsiveness and insula activation during reward anticipation are associated with genetic variants in GABRA2 in a family sample enriched for alcoholism.
(2012)
PMID:21483437
cited
GABA ... has a role ... through the fast-acting receptor complex, GABAA
confidence: 0.85
Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro.
(2012)
PMID:22486492
cited
the solution being puffed onto the cell was either 50 µM GABA ... to elicit GABAA ... responses
confidence: 0.97