ethanol group regulates DRD4

Subject: ethanol group
Relation: regulates
Object: DRD4
p-value: 0.05

Evidence from: primary | all sources

Evidence (2 sources)

Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice. (2011) PMID:21223304 cited

Binge ethanol during adolescence, but not adulthood, decreased DA-D4R mRNA and orbital frontal cortical D4DR+IR in adolescence.

confidence: 0.95

Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice. (2011) PMID:21223304 cited

44% less D4DR+IR in the OFC of P38 binge ethanol treated mice compared to P38 adolescent control mice (*p<0.05).

confidence: 0.96