trait-associated variant associated_with complex traits

Subject: trait-associated variant
Relation: associated_with
Object: complex traits
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. (2021) PMID:34475573 cited

trans-eQTL analyses to a subset of 10,317 variants previously associated with complex phenotypes

confidence: 0.90

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. (2018) PMID:29739930 cited

GWAS have been successful in robustly associating genetic loci to human complex traits; trait-associated variants are the variants identified in these studies.

confidence: 0.60

Genetic effects on gene expression across human tissues. (2017) PMID:29022597 cited

Genetic variants associated with complex traits have been suggested to be enriched for trans-eQTLs.

confidence: 0.95