cocaine interacts_with dopamine
Evidence from:
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Evidence (8 sources)
enhanced cocaine-induced dopamine levels compared to wild-type mice.
confidence: 0.80
Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications.
(2011)
PMID:22011681
cited
intravenous cocaine (which increases extracellular dopamine levels)
confidence: 0.90
Disrupted functional connectivity with dopaminergic midbrain in cocaine abusers.
(2010)
PMID:20520835
cited
cocaine binds to norepinephrine (NE) and DA transporters
confidence: 0.88
Disrupted functional connectivity with dopaminergic midbrain in cocaine abusers.
(2010)
PMID:20520835
cited
disruption of dopaminergic pathways with repeated cocaine administration
confidence: 0.85
Neural encoding of cocaine-seeking behavior is coincident with phasic dopamine release in the accumbens core and shell.
(2009)
PMID:19735286
cited
significant increases in dopamine relative to the lever press response for intravenous cocaine (F19,171 = 3.034, p < 0.001).
confidence: 0.92
Neural encoding of cocaine-seeking behavior is coincident with phasic dopamine release in the accumbens core and shell.
(2009)
PMID:19735286
cited
dopaminergic signals at the lever press for intravenous cocaine ... pre-response increase began approximately 1 s before the response
confidence: 0.90
cocaine’s main effect of blocking catecholamine reuptake at the presynaptic level
confidence: 0.95
EEG biofeedback as a treatment for substance use disorders: review, rating of efficacy, and recommendations for further research.
(2008)
PMID:18214670
cited
cocaine inhibits the reuptake of dopamine
confidence: 0.96