rs2066702 risk_factor_for alcohol dependence

Subject: rs2066702
Relation: risk_factor_for
Object: alcohol dependence
p-value: 1.5e-23

Evidence from: primary | all sources

Evidence (3 sources)

Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. (2021) PMID:32652861 primary

different functional SNP in ADH1B ... linked to alcohol dependence ... rs2066702 in AA

confidence: 0.90

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. (2015) PMID:26110981 cited

both associations replicated ... greatest effect on AD risk

confidence: 0.80

Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10. (2009) PMID:18930185 cited

ADH2 rs2066702 ... is a functional variant ... this is a risk variant.

confidence: 0.96