Cdk5 regulates DARPP-32
Evidence from:
primary |
all sources
Evidence (4 sources)
Cdk5 negatively regulates dopaminergic signaling by phosphorylating DARPP-32 on Thr-75.
confidence: 0.95
Cyclin-dependent protein kinase 5 (Cdk5) phosphorylates DARPP-32 at a different site (Thr-75).
confidence: 0.95
Cdk5-mediated DARPP-32 phosphorylation.
confidence: 0.95
PKA and Cdk5 act on the same downstream target, DARPP-32, resulting in opposing effects.
confidence: 0.93