OPRM1 associated_with alcohol dependence
Evidence from:
primary |
all sources
Evidence (3 sources)
MOR ... controls the rewarding effects of many drugs of abuse, including ... alcohol
confidence: 0.89
Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents.
(2013)
PMID:23136901
cited
association findings between this SNP and alcohol dependence are mixed
confidence: 0.60
The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks.
(2012)
PMID:22348705
cited
Several candidate genes ... have been associated with alcohol dependence, including the genes encoding opioid receptor, mu 1 (OPRM1).
confidence: 0.95