ADH1C associated_with alcohol
Evidence from:
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all sources
Evidence (8 sources)
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
including three alcohol-metabolizing genes ... ADH1C ... associated with alcohol consumption
confidence: 0.96
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
Five of the loci were previously associated with a self-reported measure of alcohol consumption: GCKR, KLB, ADH1B, ADH1C, and SLC39A8.
confidence: 0.96
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.
(2019)
PMID:30336701
cited
This region has been previously associated with alcohol consumption
confidence: 0.90
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.
(2019)
PMID:30336701
cited
identified numerous loci ... that influence alcohol consumption, including ADH1B/ADH1C/ADH5
confidence: 0.95
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
several alcohol dehydrogenase genes (ADH1B, ADH1C, ADH5) that have all previously been implicated in alcohol consumption.
confidence: 0.96
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
identify eight independent loci associated with alcohol consumption... ADH1C is one of the four loci
confidence: 0.95
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
a cluster of variants spanning the alcohol dehydrogenase genes (ADH1B, ADH1C, ADH5, ADH6, ADH7) ... linked to variation in alcohol consumption
confidence: 0.90
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
ADH1C ... significantly associated with alcohol consumption.
confidence: 0.94