APP regulates Amyloid beta

Subject: APP
Relation: regulates
Object: Amyloid beta
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Inhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complex. (2018) PMID:29777037 cited

processing of APP to Aβ

confidence: 0.93

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. (2014) PMID:24889886 cited

cleaved ... leading to release of the Aβ fragment

confidence: 0.94

New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy. (2014) PMID:25368578 cited

modulates amyloid precursor protein (APP) cleavage enzymes ... resulting in increased Aβ production

confidence: 0.90