CHRNA5 interacts_with Chrnb2

Subject: CHRNA5
Relation: interacts_with
Object: Chrnb2
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited

when combined with an additional α subunit and either a β2 ... subunit it alters several pharmacological properties of the receptor in response to nicotine

confidence: 0.90

Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011) PMID:21079997 cited

α4 and α5 nicotinic acetylcholine receptor (nAChR) subunits combine with the nAChR β2 subunit to form ... receptor

confidence: 0.95