rs588765 regulates CHRNA5

Subject: rs588765
Relation: regulates
Object: CHRNA5
p-value: —

Evidence from: primary | all sources

Evidence (4 sources)

Human Genetics of Addiction: New Insights and Future Directions. (2018) PMID:29504045 cited

noncoding CHRNA5 SNPs ... that regulate CHRNA5 RNA expression (rs588765 ...)

confidence: 0.92

Human Genetics of Addiction: New Insights and Future Directions. (2018) PMID:29504045 cited

rs588765 ... regulate CHRNA5 RNA expression ... in postmortem human PFC

confidence: 0.95

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

altered brain mRNA expression of the common (aspartate) form of CHRNA5, tagged by rs588765

confidence: 0.90

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

rs588765 ... has been shown to affect expression of CHRNA5 in EAs

confidence: 0.90