ALDH2 associated_with alcohol dependence
Evidence from:
primary |
all sources
Evidence (5 sources)
KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex.
(2016)
PMID:26202629
primary
ADH1B and ALDH2 polymorphisms with alcohol dependence
confidence: 0.95
Genetic studies of alcohol dependence in the context of the addiction cycle.
(2017)
PMID:28118990
cited
Genes involved with alcohol metabolism (aldehyde dehydrogenase [ALDH]) are also implicated
confidence: 0.94
Genetic studies of alcohol dependence in the context of the addiction cycle.
(2017)
PMID:28118990
cited
Genome-wide significant (p < 10–8) and replicable SNPs were located in the following genes ... ALDH2 ...
confidence: 0.96
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
(2017)
PMID:28485404
cited
pharmacogenetic effect of missense variants in genes ... ALDH2 ... influence ... risk of alcohol dependence.
confidence: 0.85
ALDH2 locus ... is associated with differences in both AD and alcohol consumption
confidence: 0.95