PPARα−/− mice associated_with hepatic steatosis

Subject: PPARα−/− mice
Relation: associated_with
Object: hepatic steatosis
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. (2016) PMID:26838599 cited

substantial centrilobular steatosis (figure 4C) ... confirming that hepatic PPARα expression is required.

confidence: 0.95

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. (2016) PMID:26838599 cited

During ageing, Pparα−/− mice ... developed steatosis

confidence: 0.95