SREBF2 regulates LDLR

Subject: SREBF2
Relation: regulates
Object: LDLR
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. (2021) PMID:34475573 cited

SREBF2, the gene encoding the TF SREBP-2, which increases the expression of LDLR, was downregulated

confidence: 0.96

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. (2021) PMID:34475573 cited

SREBF2 ... increases the expression of LDLR

confidence: 0.94