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Ctbp2 interacts_with SNAI1

Subject
Ctbp2
Relation
interacts_with
Object
SNAI1
p-value
Evidence from: primary | all sources

Evidence (7 sources)

CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015) PMID:25686837 cited
upregulated CtBP2 bound the PQDLSLK motif of SNAI1 in the nucleus
confidence: 0.90
CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015) PMID:25686837 cited
The presence of this motif implied that the CtBP2 protein was potentially a binding partner of the SNAI1 protein... Co‑IP results confirmed this hypothesis.
confidence: 0.96
CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015) PMID:25686837 cited
CtBP2 bound SNAI1, a well-known EMT inducer.
confidence: 0.95
CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015) PMID:25686837 cited
CtBP2 interaction motif P-DLS-K is present in the repression domains of SNAI1; CtBP2 protein bound the SNAI1 protein in the nucleus of Huh7 GLI1 cells.
confidence: 0.97
CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015) PMID:25686837 cited
we investigated the role of CtBP2 in GLI1/SNAI1 axis induced EMT.
confidence: 0.85
CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015) PMID:25686837 cited
CtBP2 ... interacts with SNAI1
confidence: 0.98
CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015) PMID:25686837 cited
SNAI1 was required for CtBP2-driven EMT
confidence: 0.70