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AUDIT-C associated_with alcohol dependence

Subject
AUDIT-C
Relation
associated_with
Object
alcohol dependence
p-value
8.2e-05
Evidence from: primary | all sources

Evidence (7 sources)

Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts. (2022) PMID:33985350 primary
AUDIT-C ... only moderately positively associated with alcohol dependence
confidence: 0.93
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019) PMID:30940813 primary
We also calculated the genetic correlations of both AUDIT-C and AUD with five traits ... including ... alcohol dependence ...
confidence: 0.95
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019) PMID:30940813 primary
genetic similarity between these alcohol-related traits is consistent with twin studies of alcohol dependence
confidence: 0.90
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019) PMID:30940813 primary
We also calculated the genetic correlations of both AUDIT-C and AUD with ... including alcohol dependence.
confidence: 0.90
Genetics of substance use disorders in the era of big data. (2021) PMID:34211176 cited
in addition to alcohol use phenotypes ... (i.e., alcohol dependence, AUD symptom count, ...)
confidence: 0.85
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
AUDIT-C modestly correlated with alcohol dependence (rg = 0.33, p < 8.2 × 10−5).
confidence: 0.94
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
We also used LDSC to examine genetic correlations between various dichotomized versions of AUDIT and DSM-IV defined alcohol dependence
confidence: 0.92