DISC1 associated_with schizophrenia
Evidence from:
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all sources
Evidence (7 sources)
genetic linkage results ... point to a broad phenotype ... schizophrenia
confidence: 0.85
Eleven genes were positional candidates ... (DISC1, ...)
confidence: 0.95
Figure 1 shows the number of times that each gene or its protein product co-occurred with schizophrenia ... DISC1 ... increased with time.
confidence: 0.95
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
(2014)
PMID:23732877
cited
The biological functions of DISC1 fit well with current aetiological concepts in SZ-related major mental illness ...
confidence: 0.92
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
(2014)
PMID:23732877
cited
DISC1 locus has not reached genome-wide significance in large-scale meta-analyses of linkage studies of SZ
confidence: 0.70
candidate genes for schizophrenia (DISC1, DAOA, and RGS4)
confidence: 0.95
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
(2009)
PMID:19065143
cited
DISC1 ... were among the most prominent candidates for either disorder
confidence: 0.90