PSEN1 risk_factor_for dementia

Subject: PSEN1
Relation: risk_factor_for
Object: dementia
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. (2017) PMID:27926491 cited

PSEN1 mutants promote ... dementia without any increase in Aβ

confidence: 0.95