NCS1 risk_factor_for cocaine
Evidence from:
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Evidence (5 sources)
Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.
(2014)
PMID:23958962
primary
There is prior association evidence of calcium system genes in cocaine dependence (e.g., neuronal calcium sensor 1, NCS1).
confidence: 0.90
Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans.
(2012)
PMID:22999924
cited
first study investigating NCS-1 as a risk gene for CA.
confidence: 0.90
Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans.
(2012)
PMID:22999924
cited
investigating NCS-1 as a risk gene for CA
confidence: 0.96
Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans.
(2012)
PMID:22999924
cited
SNPs ... NCS-1 may alter the rewarding and reinforcing behavior following cocaine abuse
confidence: 0.85
Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans.
(2012)
PMID:22999924
cited
We investigated whether polymorphisms in the NCS-1 gene confer risk to CA; a statistically significant effect was observed when AA discovery and replication samples were combined.
confidence: 0.85