paperKB
coga / coga-kb
Help
Sign in

rs9829896 regulates CREBBP

Subject
rs9829896
Relation
regulates
Object
CREBBP
p-value
0.011
Evidence from: primary | all sources

Evidence (7 sources)

KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary
consistency of rs9829896 association of expression across KAT2B, CREBBP, and OPRM1 among AAs
confidence: 0.80
KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary
trans-eQTL pattern between the protective rs9829896-C allele and reduced CREBBP gene expression
confidence: 0.90
KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary
expression of both genes was down-regulated by the protective allele for drug abuse, rs9829896-C
confidence: 0.94
KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary
the C allele being associated with lower expression of CREBBP (P=0.011) in AAs only
confidence: 0.90
KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary
rs9829896-C allele ... reduced CREBBP expression
confidence: 0.94
KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary
rs9829896 as a trans-eQTL for the CREBBP ... genes, using mRNA expression levels measured in human prefrontal cortex
confidence: 0.90
Human Genetics of Addiction: New Insights and Future Directions. (2018) PMID:29504045 cited
implicated rs9829896 as a cis-eQTL SNP ... for ... CREBBP
confidence: 0.90