rs578776 protective_against nicotine
Evidence from:
primary |
all sources
Evidence (3 sources)
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
(2009)
PMID:19706762
cited
rs578776 is significantly associated (p = 7.09×10−5, OR = 0.79 ...) and is the most strongly associated of the correlated SNPs representing this “protective” locus.
confidence: 0.96
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
(2009)
PMID:19706762
cited
The locus tagged by rs578776 ... is described as protective because the minor allele is more frequent in controls than in cases.
confidence: 0.96
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
(2009)
PMID:19706762
cited
The “protective” association at rs578776 ... is seen in European-Americans but not in African-Americans.
confidence: 0.90