OPRM1 A118G interacts_with opioid
Evidence from:
primary |
all sources
Evidence (2 sources)
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
alter the response to opioids
confidence: 0.93
Lack of association between the A118G polymorphism of the mu opioid receptor gene (OPRM1) and opioid dependence: A meta-analysis.
(2009)
PMID:23226031
cited
A118G may mediate or otherwise influence pharmacological and therapeutic responses to opioids, as evidenced by altered opioid dosage requirements
confidence: 0.70