rs997917 interacts_with naltrexone

Subject: rs997917
Relation: interacts_with
Object: naltrexone
p-value: 0.083

Evidence from: primary | all sources

Evidence (2 sources)

Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited

significant interaction between OPRK1 genotype at one locus (OPRK1^2, rs997917) and medication (naltrexone vs. placebo)

confidence: 0.95

Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited

Among Whites only, OPRK1^2 × medication interaction reduced to trend (β = 0.26, SE = 0.5, t = 1.74, p = 0.083).

confidence: 0.96