PSEN1 regulates γ-secretase

Subject: PSEN1
Relation: regulates
Object: γ-secretase
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. (2017) PMID:27926491 cited

PSEN1 mutations disrupted γ-secretase activity

confidence: 0.95