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naltrexone protective_against heavy drinking

Subject
naltrexone
Relation
protective_against
Object
heavy drinking
p-value
Evidence from: primary | all sources

Evidence (3 sources)

Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity. (2017) PMID:28134463 cited
European ancestry individuals had lower rates of relapse, longer time to heavy drinking, increased days abstinent and decreased heavy drinking days
confidence: 0.85
Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity. (2017) PMID:28134463 cited
NTX would reduce heavy drinking in this group
confidence: 0.80
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
naltrexone treatment reduces the occurrence of heavy drinking days
confidence: 0.95