Dopamine D2 receptor risk_factor_for PAU
Evidence from:
primary |
all sources
Evidence (3 sources)
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.
(2020)
PMID:32451486
primary
Ten variants were previously identified ... located in or near the following genes: DRD2 ... associated with PAU.
confidence: 0.95
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.
(2023)
PMID:38062264
cited
DRD2 expression in cerebellar hemisphere ... were also associated with PAU risk
confidence: 0.93
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.
(2023)
PMID:38062264
cited
DRD2 ... showed association with PAU by incorporating brain chromatin interaction profiles.
confidence: 0.96