GABRA2 interacts_with benzodiazepines

Subject: GABRA2
Relation: interacts_with
Object: benzodiazepines
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Mechanisms in the relation between GABRA2 and adolescent externalizing problems. (2016) PMID:25804982 cited

GABAA receptors undergo allosteric modulation by ethanol, benzodiazepines and barbituates

confidence: 0.93

GABRA2 markers moderate the subjective effects of alcohol. (2013) PMID:22501025 cited

The α-2 subunit is a key mediator of the anxiolytic effects of benzodiazepines.

confidence: 0.90

The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. (2009) PMID:19455309 cited

The α2 subunit mediates the anxiolytic effect of benzodiazepines and barbiturates

confidence: 0.90