Valproic acid protective_against CT

Subject: Valproic acid
Relation: protective_against
Object: CT
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls. (2011) PMID:21620981 cited

increasing Val dose was significantly associated with less CT in these cortical areas at age 10 years

confidence: 0.92