Gabrd regulates tonic inhibition

Subject: Gabrd
Relation: regulates
Object: tonic inhibition
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics. (2014) PMID:25538565 cited

down-regulated ... indicating decreased tonic inhibition in the caudate region.

confidence: 0.90

The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. (2009) PMID:19455309 cited

knockout models display substantially reduced/absent tonic inhibition

confidence: 0.95