varenicline associated_with abstinence

Subject: varenicline
Relation: associated_with
Object: abstinence
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. (2013) PMID:23249876 cited

Therapy randomization from baseline to EOT was to five different pharmacotherapies [NRT, BUP, PLA, VAR or combined NRT] ... and differ in prevalence of ... 6MO abstinence.

confidence: 0.90

Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited

Meta-analysis data indicate that varenicline improves the odds of abstinence two to three-fold, relative to placebo.

confidence: 0.97