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alcohol interacts_with GABAA receptor

Subject
alcohol
Relation
interacts_with
Object
GABAA receptor
p-value
0.27
Evidence from: primary | all sources

Evidence (5 sources)

Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism. (2006) PMID:17373405 primary
Alcohol acts directly on the GABAA receptor.
confidence: 0.95
Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism. (2006) PMID:17373405 primary
Researchers previously had demonstrated that alcohol directly interacts with the GABAA receptor.
confidence: 0.98
Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012) PMID:22486492 cited
of alcohol on GABAA receptors mediated by neuroactive steroids (Sanna et al., 2004).
confidence: 0.90
Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012) PMID:22486492 cited
NMDA and GABAA receptors are targets for the actions of alcohol
confidence: 0.97
Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro. (2012) PMID:22486492 cited
no significant changes were observed following acute 50 mM alcohol exposure for GABAA (n=4, p=0.27, data not shown)
confidence: 0.95