bupropion associated_with smoking cessation

the bupropion literature ... are not available in the bupropion literature ... equivalent effects of each polymorphism on smoking cessation outcome.

Participants were randomly assigned to bupropion ... to participate in a double-blind, placebo-controlled smoking cessation clinical trial.

mixed findings in the smoking cessation literature... a more broadly-based AGRS that included additional variants implicated by bupropion’s pharmacology would have improved the ability of the AGRS to moderate treatment.

The study models the complex genetics of smoking cessation and discusses pharmacogenetic predictors of bupropion response, implying bupropion’s relevance to smoking cessation.

FDA-approved approaches for smoking cessation include nicotine replacement therapy (NRT), bupropion, and varenicline.