major depressive disorder associated_with anterior cingulate cortex
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Evidence (2 sources)
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
(2018)
PMID:29700475
cited
The genetic results best match gene expression patterns in ... anterior cingulate cortex, anatomical regions that show differences between MDD cases and controls.
confidence: 0.95
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
(2018)
PMID:29700475
cited
Only brain samples showed significant enrichment ... anterior cingulate cortex are important for higher-level executive functions and emotional regulation which are often impaired in MDD.
confidence: 0.96