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rs7916403 risk_factor_for alcohol dependence

Subject
rs7916403
Relation
risk_factor_for
Object
alcohol dependence
p-value
0.042
Evidence from: primary | all sources

Evidence (6 sources)

Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary
When correcting for rs7916403, the association with alcoholism largely disappears (P = 0.098).
confidence: 0.70
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary
significant evidence for an increased risk with the number of G alleles ... OR of 1.37 ... (P = 0.042)
confidence: 0.92
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary
When testing rs7916403 under a recessive mode of genetic effect, an increased OR of 1.39 [95% CI: 1.07 – 1.81] was observed (P = 0.015).
confidence: 0.96
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary
significant association emerging in the case-control samples for intronic marker rs7916403 ... OR of 1.24
confidence: 0.94
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary
rs7916403 showing a significant relationship to the disease ... ORs of 1.32 (P = 0.036)
confidence: 0.90
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary
significant OR of 1.27 ... for the G allele in the GWAS subset (P = 0.011)
confidence: 0.90